- Job Type: Full-Time
- Function: Engineering Software
- Industry: Health Tech
- Post Date: 06/10/2026
- Website: encoded.com
- Company Address: 341 Oyster Point Blvd, South San Francisco, California 94080, US
About Encoded Therapeutics
Encoded Therapeutics is creating one-time, disease-modifying gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective targeting and regulation platform.Job Description
Encoded Therapeutics is a clinical-stage genetic medicines company dedicated to developing transformative therapies for severe CNS disorders. Our proprietary vector engineering platform combines innovative regulatory elements and payloads with AAV vectors to address debilitating and intractable CNS conditions. Our flagship clinical program, ETX101, focuses on Dravet syndrome and aims to enable selective upregulation of the SCN1A gene for lasting therapeutic benefits. Learn more at www.encoded.com.
We are seeking an experienced Engineer III, Site Engineering & Facilities to join our rapidly growing team. This role will focus on ensuring the optimal operation, maintenance, and improvement of our site infrastructure and facilities in support of scientific and operational excellence. The successful candidate will work collaboratively across departments to lead engineering projects and maintain a safe and efficient working environment.
Responsibilities
- Lead and manage site engineering projects including preventive maintenance, repairs, and upgrades of facility systems.
- Coordinate with vendors and contractors for site and equipment installations, maintenance, and troubleshooting.
- Ensure compliance with environmental health and safety regulations and contribute to continuous improvement initiatives.
- Perform or oversee building systems monitoring, including HVAC, electrical, plumbing, and utilities.
- Support facilities-related capital projects from planning through execution and closeout.
- Collaborate with cross-functional teams to support site operations and ensure facility readiness.
- Maintain documentation, records, and reports related to site engineering and facilities management.
- Assist in the development and enforcement of site safety protocols and procedures.
Requirements
- Education: Bachelor’s degree in Engineering (Mechanical, Chemical, or Bioengineering preferred).
- Experience: 5-9 years of directly relevant experience in the biotech, pharmaceutical, or gene therapy space.
- Technical Knowledge: Proven expertise in facility, process, or manufacturing engineering. Single-use technology and viral vector manufacturing experience is highly preferred.
- Regulatory Fluency: Deep understanding of cGMP systems and FDA/EU regulations.
- Operational Flexibility: Ability to provide on-call or in-person support for batch processing operations.
- Soft Skills: Strong troubleshooting, organizational, and interpersonal skills. Must be a proactive team player.
- Travel: Ability to travel up to 10% for vendor visits or headquarters requirements.
Benefits
- Comprehensive benefits package, including competitive employer premium contributions
- Meaningful stock option grants
- PTO, sick time, and holiday pay
- Generous Parental Leave program
- Pre-tax medical and dependent care programs
- STD, LTD, Life and AD&D
- Professional development opportunities
- Team-building events
- Fully stocked kitchen
Employees (and their families) may obtain medical, dental, vision and basic life insurance benefits through the company and enroll in our company’s 401k plan. Employees will also accrue vacation time off and paid sick time off and may become eligible for paid parental leave. Employees will also enjoy designated paid holidays throughout the calendar year.
Encoded is an Equal Opportunity Employer and prohibits discrimination and harassment of any kind. Encoded is committed to the principle of equal employment opportunity for all employees and to providing employees with a work environment free of discrimination and harassment. All employment decisions at Encoded are based on business needs, job requirements and individual qualifications, without regard to race, religion or belief, color, national origin, gender, status as a protected veteran, status as an individual with a disability, or any other status protected by the laws or regulations in the location in which we operate. Encoded will not tolerate discrimination or harassment based on any of these characteristics. Encoded encourages applicants of all ages.
If you need assistance or an accommodation due to a disability, you may call us at +1 650-491-0272.